I might have to slightly reconsider my stance on multi-effects - although I would never base a setup around it as the main part, having it there's pretty cool. I only put this board together this afternoon, so I've only been playing with one sound out of it, and the Zoom pedal is doing a 8ve harmony and some reverb, with delay and more reverb from my DD-6 and RE-20 and third harmonies from the Whammy. Ronald Jones ftw.
And the stereo outs from the Zoom are feeding my main amp, and that little Fender Mini Deluxe dealy just on top of the board. I can pick that one up, switch it on, and hold it up to the pickups for some really harsh feedback, which goes out into my main amp also. Doing all this while playing with the coin is probably the most exciting thing I've done with my guitar

There is no problem so bad that you can't make it worse.